Cape Coral is a city in Lee County, Florida, United States. The population was 102,286 at the 2000 census. According to the U.S Census estimates of 2005, the city had a population of 140,010. making it the largest city in Southwest Florida. Cape Coral is one of two major cities that make up the Cape Coral-Fort Myers MSA, the other being Fort Myers. As of July 1, 2005, the population estimate for the metropolitan area was 544,758.

According to the United States Census Bureau, the city has a total area of 298.1 km² (115.1 mi²), making it the second largest in Florida. 272.4 km² (105.2 mi²) of it is land and 25.7 km² (9.9 mi²) of it (8.61%) is water. As of the census of 2000, there were 109,286 people, 40,768 households, and 30,209 families residing in the city. The population density was 375.4/km² (972.4/mi²). There were 45,653 housing units at an average density of 167.6/km² (434.0/mi²). The racial makeup of the city was 93.01% White, 2.00% African American, 0.25% Native American, 0.92% Asian, 0.05% Pacific Islander, 2.20% from other races, and 1.56% from two or more races. Hispanic or Latino of any race were 8.33% of the population.