Bryan is a city in Brazos County, Texas, United States. As of the 2000 census, the city had a total population of 65,660. It is the county seat of Brazos County and is located in the heart of the Brazos Valley (Southeast Central Texas), an area often referred to as "Aggieland". The city is centrally located, approximately equidistant from three of the 10 largest cities in the United States. It is 92 miles north-northwest of Houston, 166 miles northeast of San Antonio and 169 miles south of Dallas. It is 104 miles east of Austin, the state capital of Texas. 75% of the Texas and Louisiana populations (13.1 million people) live within 3.5 driving hours of Bryan.

According to the United States Census Bureau, the city has a total area of 112.5 km˛ (43.4 mi˛). 112.3 km˛ (43.3 mi˛) of it is land and 0.2 km˛ (0.1 mi˛) of it (0.21%) is water. As of the census of 2000, there were 65,660 people, 23,759 households, and 14,873 families residing in the city. The population density was 584.9/km˛ (1,515.2/mi˛). There were 25,703 housing units at an average density of 229.0/km˛ (593.1/mi˛). The racial makeup of the city was 64.65% White, 17.72% African American, 0.40% Native American, 1.65% Asian, 0.08% Pacific Islander, 13.32% from other races, and 2.17% from two or more races. Hispanic or Latino of any ethnicity/nationality were 27.83% of the population.