Brazoria County is a county in the U.S. state of Texas located on the Gulf Coast within the metropolitan area. Its county seat is Angleton, and it's largest city is Pearland. As of the 2000 U.S. Census, the county had a population of 241,767. Brazoria County, like nearby Brazos County, takes its name from the Brazos River, which flows through it. Anglo-Texas began in Brazoria County when the first of Stephen F. Austin's authorized 300 American settlers arrived at the mouth of the Brazos River in 1821. Many of the events leading to the Texas Revolution developed in Brazoria County.

According to the U.S. Census Bureau, the county has a total area of 4,137 km² (1,597 mi²). 3,591 km² (1,386 mi²) of it is land and 547 km² (211 mi²) of it (13.21%) is water. As of the census² of 2000, there were 241,767 people, 81,954 households, and 63,104 families residing in the county. The population density was 67/km² (174/mi²). There were 90,628 housing units at an average density of 25/km² (65/mi²). The racial makeup of the county was 77.09% White, 8.50% Black or African American, 0.53% Native American, 2.00% Asian, 0.03% Pacific Islander, 9.63% from other races, and 2.22% from two or more races. 22.78% of the population were Hispanic or Latino of any race.